Our Technology

We design synthetic promoters using natural gene regulatory sequences that are cell-selective or conditionally active  to client specifications

We have developed a platform of algorithms and know-how that is engineered to run meta-analyses on diverse functional genomics datasets and enable us to:

Isolate Cell-Selective and Conditional Enhancers


Identify short gene regulatory motifs in the genome that are active in specific cell types or active under specific environmental conditions


  • To generate libraries of small genetic parts that can control gene expression in specific cell types or in response to different types of stimuli

Create Novel Synthetic Gene Expression Vectors


Engineer genetic circuitry from these motifs to create constructs that allow cell-type selective, controllable gene expression


  • By combining multiple genetic parts from our library to construct synthetic promoters and expression vectors that meet a target activity profile

Work to Client Demand for Custom Gene Control


Rationally-designed to confer more effective and tighter control of gene payload expression to a precise specification


  • Unique sequence combinations, not found naturally, and so can be patented and used to create an effective IP estate to protect a product or process

How we work with our clients

We work with our clients to design synthetic promoters and gene expression vectors that control genes to a client's target profile, i.e., promoters of a certain size, active at a certain level, specific to target cell types, or in response to a stimulus.



We have a flexible business model that is tailored to the size and needs of our clients, and to the industry that they operate in. Typically, we charge a technology access fee for our designs, which is then followed by development and commercial milestones.


Our clients retain ownership of the custom-designed promoter / gene expression construct IP and rights to apply for patents covering the promoter designs that meet the target profile. This enables effective IP protection for our clients' products and processes.



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