Chromatin Bioscience Announces Collaboration with Purespring Therapeutics

Chromatin Bioscience is pleased to announce an ongoing research collaboration with Purespring Therapeutics, a precision nephrology company leading the development of targeted, first-in-class genetic therapies to preserve kidney function. The collaboration leverages Chromatin Bio's proprietary synthetic promoter design platform, ChromatinLENS, to develop highly cell-selective promoters tailored to support Purespring's innovative gene therapy pipeline.

The partnership aims to enable precise and durable gene expression in target cell types relevant to Purespring's therapeutic strategy. While specific program details remain confidential, the project is designed to enhance the safety and efficacy of gene delivery through the integration of rationally designed synthetic promoters.

"Purespring's approach to gene therapy aligns well with our mission to provide precise gene control systems that support advanced, tissue-targeted therapeutics," said Michael Roberts, CEO and Founder of Chromatin Bioscience. "We are excited to support their efforts with our platform and help unlock the full therapeutic potential of next-generation gene therapies."

Chromatin Bioscience's ChromatinLENS platform identifies highly specific gene regulatory elements from the dark genome and integrates them into synthetic promoters optimised for target cell selectivity and expression durability. These promoters are a critical component in gene therapies where spatial and temporal control of transgene expression is essential for therapeutic success.

This collaboration with Purespring represents another milestone in Chromatin Bioscience's growing network of partnerships across the gene therapy landscape.